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Título : Frequentist, bayesian analysis and complementary statistical tools for geriatric and rehabilitation fields : are traditional null-hypothesis significance testing methods sufficient?
Autor : Nascimento, Dahan da Cunha
Rolnick, Nicholas
Almeida, Isabella da Silva
Cipriano Junior, Gerson
Durigan, João Luiz Quagliotti
metadata.dc.identifier.orcid: http://orcid.org/0000-0002-6580-9404
http://orcid.org/0000-0001-9778-2800
http://orcid.org/0000-0001-6323-7003
metadata.dc.contributor.affiliation: Universidade Católica de Brasília, Physical Education Department
Lehman College, The Human Performance Mechanic Department
Universidade de Brasília, Faculdade de Ceilândia, Laboratory of Muscle and Tendon Plasticity
Universidade de Brasília, Faculdade de Ceilândia, Graduate Program in Rehabilitation Science
Universidade de Brasília, Faculdade de Ceilândia, Laboratory of Muscle and Tendon Plasticity
Assunto:: Estatística
Análise bayesiana
Ferramentas de estudo
Fecha de publicación : feb-2024
Editorial : Dovepress
Citación : NASCIMENTO, Dahan da Cunha et al. Frequentist, bayesian analysis and complementary statistical tools for geriatric and rehabilitation fields: are traditional null-hypothesis significance testing methods sufficient?. Clinical Interventions in Aging, [S. l.], v. 19, p. 277-287, 2024. DOI: https://doi.org/10.2147/CIA.S441799. Disponível em: https://www.dovepress.com/frequentist-bayesian-analysis-and-complementary-statistical-tools-for--peer-reviewed-fulltext-article-CIA. Acesso em: 19 maio 2026.
Abstract: Null hypothesis significant testing (NHST) is the dominant statistical approach in the geriatric and rehabilitation fields. However, NHST is routinely misunderstood or misused. In this case, the findings from clinical trials would be taken as evidence of no effect, when in fact, a clinically relevant question may have a “non-significant” p-value. Conversely, findings are considered clinically relevant when significant differences are observed between groups. To assume that p-value is not an exclusive indicator of an association or the existence of an effect, researchers should be encouraged to report other statistical analysis approaches as Bayesian analysis and complementary statistical tools alongside the p-value (eg, effect size, confidence intervals, minimal clinically important difference, and magnitude-based inference) to improve interpretation of the findings of clinical trials by presenting a more efficient and comprehensive analysis. However, the focus on Bayesian analysis and secondary statistical analyses does not mean that NHST is less important. Only that, to observe a real intervention effect, researchers should use a combination of secondary statistical analyses in conjunction with NHST or Bayesian statistical analysis to reveal what p-values cannot show in the geriatric and rehabilitation studies (eg, the clinical importance of 1kg increase in handgrip strength in the intervention group of long-lived older adults compared to a control group). This paper provides potential insights for improving the interpretation of scientific data in rehabilitation and geriatric fields by utilizing Bayesian and secondary statistical analyses to better scrutinize the results of clinical trials where a p-value alone may not be appropriate to determine the efficacy of an intervention.
metadata.dc.description.unidade: Faculdade de Ciências e Tecnologias em Saúde (FCTS) – Campus UnB Ceilândia
metadata.dc.description.ppg: Programa de Pós-Graduação em Ciências e Tecnologias em Saúde
Programa de Pós-Graduação em Ciências da Reabilitação
Licença:: 2024 Nascimento et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/ terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
DOI: https://doi.org/10.2147/CIA.S441799
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