Title:	The control and prevention of COVID-19 transmission in children : a protocol for systematic review and meta-analysis
Authors:	Medeiros, Gidyenne Christine Bandeira Silva de Nunes, Ana Clara de França Azevedo, Kesley Pablo Morais de Oliveira Segundo, Victor Hugo de Santos, Gilberto Martins Mata, Ádala Nayana de Sousa Pimenta, Isac Davidson Bezerra, Isaac Newton Machado Braga, Liliane Pereira Capucho, Helaine Carneiro Piuvezam, Márcia Regina Barbosa Filho, Valter Cordeiro Leitão, José Carlos Martínez, Daniel Guillén Piuvezam, Grasiela
metadata.dc.identifier.orcid:	http://orcid.org/0000-0001-5225-385X http://orcid.org/0000-0001-6749-3899 https://orcid.org/0000-0002-7849-2661 http://orcid.org/0000-0002-4596-9590 http://orcid.org/0000-0001-8296-3852 http://orcid.org/0000-0003-3929-2082 https://orcid.org/0000-0002-8246-0603 http://orcid.org/0000-0002-5860-6588 http://orcid.org/0000-0001-7994-4001 http://orcid.org/0000.0003-2134-1667 http://orcid.org/0000-0002-4769-4068 http://orcid.org/0000-0003-1798-2496 http://orcid.org/0000-0003-4968-1364 http://orcid.org/0000-0002-2343-7251
Assunto::	Crianças Adolescentes Covid-19 Infecção por coronavírus - transmissão
Issue Date:	31-Jul-2020
Publisher:	Wolters Kluwer Health, Inc.
Citation:	MEDEIROS, Gidyenne Christine Bandeira Silva de et al. The control and prevention of COVID-19 transmission in children: a protocol for systematic review and meta-analysis. Medicine, v. 99, n. 3, e21393, 31 jul. 2020. DOI: http://dx.doi.org/10.1097/MD.0000000000021393. Disponível em: https://journals.lww.com/md-journal/Fulltext/2020/07310/The_Control_and_Prevention_of_COVID_19.62.aspx. Acesso em: 06 abr. 2021.
Abstract:	Background: The pandemic following the rapid spread of the new SARS-CoV-2 virus has hit all continents and caused thousands of deaths worldwide. Evidence has been published on epidemiological and clinical characteristics of population groups considered at risk; however, information for the other population groups, especially for the child population, is needed. In this context, this protocol describes a systematic review that will aim to identify the evidence on control and prevention of COVID-19 transmission among children and adolescents, as well as to describe the epidemiological profile and clinical and immunological characteristics of COVID-19 in this population. Methods: This protocol will be developed in accordance with PRISMA-P. The searches will be conducted in PubMed, Web of Science, ScienceDirect, EMBASE, and Scopus, seeking clinical trials. Observational studies and case reports with Children and adolescents (≤19 years) infected with SARS-CoV-2 will be included whether they report information on the control of prevention and COVID-19 transmission. Two independent researchers will perform the selection of articles, removal of duplication, and screening by Rayyan QCRI application. Cochrane's RoB 2.0, ROBINS-I, and CASP tools will be used to assess the risk of bias. Meta-analysis, subgroup analyses, and/or descriptive analyses will be carried out based on the data conditions included. Results: A high-quality synthesis of the available evidences on the epidemiological profile, the clinical and immunological characteristics involved in children, and adolescents diagnosed with COVID-19, as well as the participation of this population in the transmission dynamics of SARS-CoV-2 will be provided. Conclusion: This systematic review has an important relevance in the current context because it has a great potential to help the development of new control and prevention strategies in the pediatric population.
Licença::	Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
DOI:	http://dx.doi.org/10.1097/MD.0000000000021393
Appears in Collections:	Artigos publicados em periódicos e afins UnB - Covid-19

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