Title:	Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil
Authors:	Vernal, Sebastian Bueno Filho, Roberto Gomes, Ciro Martins Roselino, Ana Maria
metadata.dc.identifier.orcid:	http://orcid.org/0000-0002-2709-1825
Assunto::	Leishmaniose Hanseníase Leishmaniose cutânea
Issue Date:	2019
Publisher:	Sociedade Brasileira de Medicina Tropical - SBMT
Citation:	VERNAL, Sebastian et al. Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: a case series in Southeastern Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 52, e20180172, 2019. DOI: https://doi.org/10.1590/0037-8682-0172-2018. Disponível em: http://scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100633. Acesso em: 23 jan. 2020.
Abstract:	INTRODUCTION: American tegumentary leishmaniasis (ATL) and leprosy share common areas of prevalence, but reports of coinfection are scarce. METHODS: We report a series of 9 ATL-leprosy cases and discuss the association. An integrative diagram to analyze the clinico-immunological features of coinfection with both diseases. RESULTS: Nine patients with leishmaniasis (5 cutaneous, 3 mucocutaneous, 1 disseminated case) exhibited concurrent infection with distinct clinical forms of leprosy. Our diagram-based analysis evidenced a divergent clinico-immunological spectrum for each disease in 8 out of 9 cases. CONCLUSIONS: The spectrum of ATL-leprosy comorbidity suggests that the host has a specific immune response against each pathogen.
metadata.dc.description.unidade:	Faculdade de Medicina (FMD)
DOI:	https://doi.org/10.1590/0037-8682-0172-2018
Appears in Collections:	Artigos publicados em periódicos e afins

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