Title:	Epidemiological features, echocardiographic findings, and parasite load in patients with Chagas disease
Authors:	Arruda, Hilda Maria Benevides da Silva de Ribeiro, Marcelle Araújo Silva, Antonia Marilene da Vasconcelos, Daniel Oliveira, Maria Regina Fernandes de Noronha, Elza Ferreira
metadata.dc.identifier.orcid:	http://orcid.org/0000-0002-2338-4102
Assunto::	Epidemiologia Hospitais universitários Chagas, Doença de
Issue Date:	2019
Publisher:	Sociedade Brasileira de Medicina Tropical - SBMT
Citation:	Arruda, Hilda Maria Benevides da Silva de et al. Epidemiological features, echocardiographic findings, and parasite load in patients with Chagas disease. Revista da Sociedade Brasileira de Medicina Tropical, v. 52, e20180541, 2019. DOI: https://doi.org/10.1590/0037-8682-0541-2018. Disponível em: http://scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100344. Acesso em: 23 jan. 2020.
Abstract:	INTRODUCTION Chagas disease is a major public health problem that is endemic in Brazil and Latin America. This study aimed to determine the socioeconomic, demographic, and clinical characteristics of 171 patients (mean age, 45 years; female, 65%) with Chagas disease at Hospital Universitário de Brasília, Federal District, Brazil. METHODS We implemented this cross-sectional study using a clinical epidemiological questionnaire, electrocardiography, echocardiography, and quantitative detection of Trypanosoma cruzi DNA in blood using qRT-PCR. RESULTS Among the patients, 26.3% had a full elementary education, and 13.2% were illiterate. Most (63.6%) were economically classified as class C, and 51.5% were born in Bahia state. A total of 62.0% participants reported previous contact with the triatomine bug. The clinical forms of the disease were indeterminate (69.51%), cardiac (15.24%), digestive (10.37%), and mixed (4.88%). The most common electrocardiographic abnormality was complete right bundle branch block in association with a divisional anterosuperior block. Only 14.6% of the patients complied with benznidazole medication for at least 60 days, and 164 of them were assessed by echocardiography. The parasite load was positive in 56% of the patients. CONCLUSIONS: Chagas disease affected mostly women, with the indeterminate chronic form of the disease.
metadata.dc.description.unidade:	Faculdade de Medicina (FMD)
Licença::	OPEN ACCESS - https://creativecommons.org/licenses/by/4.0/ - (CC BY).
DOI:	https://doi.org/10.1590/0037-8682-0541-2018
Appears in Collections:	Artigos publicados em periódicos e afins

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