Title:	Nasal involvement in obstructive sleep apnea syndrome
Authors:	Michels, Daniel de Sousa Rodrigues, Amanda da Mota Silveira Nakanishi, Márcio Sampaio, André Luiz Lopes Venosa, Alessandra Ramos
Assunto::	Síndrome das apnéias do sono Otorrinolaringologia
Issue Date:	Nov-2014
Publisher:	Hindawi
Citation:	MICHELS, Daniel de Sousa et al. Nasal involvement in obstructive sleep apnea syndrome. International Journal of Otolaryngology, Londres, v. 2014, p. 1-8, nov. 2014. Disponível em: <https://www.hindawi.com/journals/ijoto/2014/717419/>. Acesso em: 7 dez. 2017. doi: http://dx.doi.org/10.1155/2014/717419.
Abstract:	Numerous studies have reported an association between nasal obstruction and obstructive sleep apnea syndrome (OSAS), but the precise nature of this relationship remains to be clarified. This paper aimed to summarize data and theories on the role of the nose in the pathophysiology of sleep apnea as well as to discuss the benefits of surgical and medical nasal treatments. A number of pathophysiological mechanisms can potentially explain the role of nasal pathology in OSAS. These include the Starling resistor model, the unstable oral airway, the nasal ventilatory reflex, and the role of nitric oxide (NO). Pharmacological treatment presents some beneficial effects on the frequency of respiratory events and sleep architecture. Nonetheless, objective data assessing snoring and daytime sleepiness are still necessary. Nasal surgery can improve the quality of life and snoring in a select group of patients with mild OSAS and septal deviation but is not an effective treatment for OSA as such. Despite the conflicting results in the literature, it is important that patients who are not perfectly adapted to CPAP are evaluated in detail, in order to identify whether there are obstructive factors that could be surgically corrected.
metadata.dc.description.unidade:	Faculdade de Medicina (FMD)
Licença::	International Journal of Otolaryngology - Copyright © 2014 Daniel de Sousa Michels et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 3.0). Fonte: https://www.hindawi.com/journals/ijoto/2014/717419/. Acesso em: 7 dez. 2017.
DOI:	http://dx.doi.org/10.1155/2014/717419
Appears in Collections:	Artigos publicados em periódicos e afins

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