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Title: Antimicrobial and cytotoxic activities screening of some Brazilian medicinal plants used in Governador Valadares district
Other Titles: Triagem das atividades antimicrobiana e citotóxica de algumas plantas medicinais brasileiras usadas na cidade de Governador Valadares
Authors: Brasileiro, Beatriz Gonçalves
Pizziolo, Virgínia Ramos
Raslan, Délio Soares
Jamal, Claudia Masrouah
Silveira, Dâmaris
Assunto:: Medicina popular
Plantas medicinais
Toxidade - testes
Microorganismos - efeito das drogas
Artemia salina
Issue Date: Apr-2006
Citation: BRASILEIRO, Beatriz Gonçalves et al. Antimicrobial and cytotoxic activities screening of some Brazilian medicinal plants used in Governador Valadares district. Revista brasileira de ciências farmacêuticas, São Paulo, v. 42, n. 2, vp. 195-202, abr./ jun. 2006. Disponível em: <http://www.scielo.br/pdf/rbcf/v42n2/a04v42n2.pdf>. Acesso em: 6 jan. 2011. doi: http://dx.doi.org/10.1590/S1516-93322006000200004.
Abstract: Ethanol extracts from medicinal plants commonly used by Governador Valadares people were tested for antimicrobial activity and cytotoxicity (BST assay). The field survey was conducted during the years 1997-2000 by means of direct interviews with healing men (“raizeiros”) who showed familiarity with local used remedies. A total of 33 crude extracts from 32 plant species was studied. Ten extracts (Costus pisonis, Cymbopogon nardus, Eclipta alba, Eleutherine bulbosa, Erigium foetidium, Euphorbia tirucalli, Mikania hirsutissima, Momordica charantia, Solidago microglossa and Plectranthus ornatus) presented brine shrimp toxicity (LD50<1000 ppm). Thirteen extracts presented antimicrobial activity against Staphylococcus aureus: E. alba, Scoparia sp., Arctium lappa, Chammomila tinctoria, E. bulbosa, M. hirsutíssima, S. microglossa, Stachytarpheta dichotoma, Pffafia glomerata, Stenorrhyrchnus lanceolatum, Vernonia condensata and Lippia alba. None extract presented activity against Escherichia coli.
DOI: http://dx.doi.org/10.1590/S1516-93322006000200004
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