Titre:	Atividade simpática, parassimpática e metabólica influenciadas pelo comportamento da distribuição do suporte de peso em pé adquirido na condição de hemiparesia crônica
Autre(s) titre(s):	Sympatetic, parasimpatetic and metabolic activities influenced by weight-bearing distribution behavior during upright position acquired in the chronic hemiparesis condition
Auteur(s):	Ramos, Gabrielly Craveiro
Orientador(es)::	Gomes, Claure Nain Lunardi
Coorientador(es)::	Martins, Emerson Fachin
Assunto::	Acidente vascular cerebral Frequência cardíaca Sistema nervoso Óxido nítrico
Date de publication:	25-jan-2016
Data de defesa::	25-sep-2015
Référence bibliographique:	RAMOS, Gabrielly Craveiro. Atividade simpática, parassimpática e metabólica influenciadas pelo comportamento da distribuição do suporte de peso em pé adquirido na condição de hemiparesia crônica. 2015. xi, 83 f, il. Tese (Doutorado em Ciências e Tecnologias em Saúde)—Universidade de Brasília, Brasília, 2015.
Abstract:	Introduction: The strokeis the most frequent cause of chronic neurological disability in adults. The cerebralvascular disorder can generate changes whether in the postural control, observed by asymmetry in the distribution of standing weight-bearing, or in the cardiac autonomic control through the sympathetic and parasympathetic response, changing the heart rate variability (HRV). Then the combined changes promoted by the encephalic injury could in increased energy expenditure, which may result in a condition of oxidative stress, observed by the amount of serum nitrate. Objective: To determine whether the sympathetic and parasympathetic nervous activities, and metabolic activity observed by serum nitrate levels are change by the type of weight-bearing standing chronically adopted by stroke survivors. Methods: The cross-sectional design was applied in the case-control type for 51 subjects with chronic hemiparesis whose age and body mass index (BMI) were used to normalize 57 others healthy subjects. All was men between 40 and 70 years. The hemiparetic subjects under went measurements computed baropodometry, to identify the type of standing weight-bearing defined by calculating the ratio of symmetry (RS). Subsequently, hemiparesis group was split in to three subgroups presented by distribution types: symmetric (n=7), asymmetric overloading the nonpredominantly used hemibody (NPUH, n=7)) and asymmetric overloading the predominantly used in the hemibody (PUH, n=5). Controls were randomly separated to compose the reference subgroup (n=7). To characterize the sympathetic and parasympathetic response from HRV, we calculated derived functions from HRV in the time and frequency domain in supine, sitting and standing postures for 5 minutes each posture and a rest interval of two minutes between them. At last, we extracted from the blood samples the level of serum nitrate. Results: Statistical tests did not detect significant correlation between age and RMSSD (parassimpatic) values, although the RMSSD symmetric subgroup has shown a trend to increase during upright posture (0.05<p<0.10) to 3 times (14.7 to 47.6) compared to the reference sub-group. In the sitting posture, thr variable low frequency (BF) decreased significantly in the symmetric subgroup (0.05 ± 0.01) compared to the reference subgroup (0.08±0.02). While, in the standing posture, a significant increase in righ frequency (AF) was detected in the symmetric subgroup (0.26±0.076) when compared to the reference sub-group (0.173±0.056). None significant differences was observed from nitrate serum concentration. Conclusion: Our results suggest a possible association between parasympathetic activity and types of weight-bearing distribution, mainly observed in the postures demanding more antigravity-effort in the subjects with hemiparesis, which maintain a more symmetrical distribution of this support, suggesting that the individuals from the symmetric distribution coul be leading to adaptate the response observed in the cardiac performance.
metadata.dc.description.unidade:	Faculdade de Ciências e Tecnologias em Saúde (FCTS) – Campus UnB Ceilândia
Description:	Tese (doutorado)—Universidade de Brasília, Faculdade de Ceilândia, Programa de Pós-Graduação em Ciências e Tecnologia em Saúde, 2015.
metadata.dc.description.ppg:	Programa de Pós-Graduação em Ciências e Tecnologias em Saúde
Licença::	A concessão da licença deste item refere-se ao termo de autorização impresso assinado pelo autor com as seguintes condições:Na qualidade de titular dos direitos de autor da publicação, autorizo a Universidade de Brasília e o IBICT a disponibilizar por meio dos sites www.bce.unb.br, www.ibict.br, http://hercules.vtls.com/cgi-bin/ndltd/chameleon?lng=pt&skin=ndltd sem ressarcimento dos direitos autorais, de acordo com a Lei nº 9610/98, o texto integral da obra disponibilizada, conforme permissões assinaladas, para fins de leitura, impressão e/ou download, a título de divulgação da produção científica brasileira, a partir desta data.
DOI:	http://dx.doi.org/10.26512/2015.09.T.19272
Collection(s) :	Teses, dissertações e produtos pós-doutorado

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