| Campo DC | Valor | Idioma |
|---|
| dc.contributor.author | Rubens, Rebeca Siqueira | - |
| dc.contributor.author | Arruda, Isabel de Souza Andrade | - |
| dc.contributor.author | Almeida, Rosane Mansan | - |
| dc.contributor.author | Nóbrega, Yanna Karla de Medeiros | - |
| dc.contributor.author | Carneiro, Maiara dos Santos | - |
| dc.contributor.author | Dalmolin, Tanise Vendruscolo | - |
| dc.date.accessioned | 2024-06-20T13:11:21Z | - |
| dc.date.available | 2024-06-20T13:11:21Z | - |
| dc.date.issued | 2024-01-04 | - |
| dc.identifier.citation | RUBENS, Rebeca Siqueira et al. Challenges in the detection of polymyxin resistance: from today to the future. Microorganisms, v. 12, n. 1, 2024. DOI: https://doi.org/10.3390/microorganisms12010101. Disponível em: https://www.mdpi.com/2076-2607/12/1/101. | pt_BR |
| dc.identifier.uri | http://repositorio2.unb.br/jspui/handle/10482/48340 | - |
| dc.language.iso | eng | pt_BR |
| dc.publisher | MDPI | pt_BR |
| dc.rights | Acesso Aberto | pt_BR |
| dc.title | Challenges in the detection of polymyxin resistance : from today to the future | pt_BR |
| dc.type | Artigo | pt_BR |
| dc.subject.keyword | Suscetibilidade a antimicrobianos | pt_BR |
| dc.subject.keyword | Polimixinas | pt_BR |
| dc.subject.keyword | Bactérias gram-negativas | pt_BR |
| dc.rights.license | © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). | pt_BR |
| dc.identifier.doi | https://doi.org/10.3390/microorganisms12010101 | pt_BR |
| dc.description.abstract1 | Antimicrobial resistance is known to be one of the greatest global threats to human health, and is one of the main causes of death worldwide. In this scenario, polymyxins are last-resort antibiotics to treat infections caused by multidrug-resistant bacteria. Currently, the reference test to evaluate the susceptibility of isolates to polymyxins is the broth microdilution method; however, this technique has numerous complications and challenges for use in laboratory routines. Several phenotypic methods have been reported as being promising for implementation in routine diagnostics, including the BMD commercial test, rapid polymyxin NP test, polymyxin elution test, culture medium with polymyxins, and the Polymyxin Drop Test, which require materials for use in routines and must be easy to perform. Furthermore, Sensititre®, molecular tests, MALDI-TOF MS, and Raman spectroscopy present reliable results, but the equipment is not found in most microbiology laboratories. In this context, this review discusses the main laboratory methodologies that allow the detection of resistance to polymyxins, elucidating the challenges and perspectives. | pt_BR |
| dc.identifier.orcid | https://orcid.org/0000-0001-8545-069X | pt_BR |
| dc.identifier.orcid | https://orcid.org/0000-0001-9975-6470 | pt_BR |
| dc.contributor.affiliation | Universidade de Brasília, Faculdade de Ciências da Saúde, Departamento de Farmácia, Laboratório de Microbiologia e Imunologia Clínica (LabMIC) | pt_BR |
| dc.contributor.affiliation | Universidade de Brasília, Faculdade de Ciências da Saúde, Departamento de Farmácia, Laboratório de Microbiologia e Imunologia Clínica (LabMIC) | pt_BR |
| dc.contributor.affiliation | Universidade de Brasília, Faculdade de Ciências da Saúde, Departamento de Farmácia, Laboratório de Microbiologia e Imunologia Clínica (LabMIC) | pt_BR |
| dc.contributor.affiliation | Universidade de Brasília, Faculdade de Ciências da Saúde, Departamento de Farmácia, Laboratório de Microbiologia e Imunologia Clínica (LabMIC) | pt_BR |
| dc.contributor.affiliation | Centro de Medicina Laboratorial, Farroupilha | pt_BR |
| dc.contributor.affiliation | Universidade de Brasília, Faculdade de Ciências da Saúde, Departamento de Farmácia, Laboratório de Microbiologia e Imunologia Clínica (LabMIC) | pt_BR |
| dc.description.unidade | Faculdade de Ciências da Saúde (FS) | pt_BR |
| dc.description.unidade | Departamento de Farmácia (FS FAR) | pt_BR |
| Aparece nas coleções: | Artigos publicados em periódicos e afins
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