Título:	Fat globules diameter in infant formulas
Autor(es):	Mendonça, Márcio Antônio Arruda, Sandra Fernandes Alencar, Ernandes Rodrigues de Araújo, Wilma Maria Coelho
Afiliação do autor:	University of Brasília, Faculty of Agronomy and Veterinary Medicine University of Brasília, College of Health Sciences, Department of Nutrition Federal University of Viçosa, Agricultural Engineering Department University of Brasília, College of Health Sciences, Department of Nutrition
Assunto:	Fórmulas nutricionais Bebês Glóbulos de gordura Ácidos graxos Leite materno
Data de publicação:	7-Mar-2024
Editora:	Elsevier Inc.
Referência:	MENDONÇA, Márcio Antônio et al. Fat globules diameter in infant formulas. Nutrition, [S. l.], 112264, maio 2024. DOI: https://doi.org/10.1016/j.nut.2023.112264.
Abstract:	Objectives The lipid fraction, fatty acid profile as well as the diameter of fat globules of infant formulas (IF) still shows great differences to human milk. These characteristics influence fat digestion and consequently, the development and health of infants. This study evaluated the diameter of fat globules in infant formulas and compared them with human milk sample. Methods The diameter of fat globules of ten IF and human milk samples was determined using scanning electron microscopy. Results The Starter Infant Formula (StIF) was the only one that showed a mean diameter value (3.52 ± 2.17 µm) similar to that obtained for human milk (3.44 ± 1.68 µm). The StIF showed the highest values of volume-surface D3,2 (6.13 µm) and volume-weighted D4,3, (7.05 µm) mean diameters among the infant formulas analyzed, and close to those obtained for Human milk sample (5.16 and 5.98µm, respectively). The infant formulas Whey Protein Partially Hydrolyzed (WPPHIF), Soy Protein Isolate-based (SPIIF), Whey Protein Extensively Hydrolyzed (WPEHIF) and Thickened with Pregelatinized Starch (IFTPGS) had the lowest mean diameters of fat globules 0.64 ± 0.22, 0.70 ± 0.19, 1.06 ± 0.34 and 1.22 ± 0.48 µm, respectively. Conclusion The analysis of principal components showed that none of the analyzed infant formulas had similarity with the diameter of fat globules and the fatty acid profile of human milk.
Unidade Acadêmica:	Faculdade de Ciências da Saúde (FS) Departamento de Nutrição (FS NUT) Faculdade de Agronomia e Medicina Veterinária (FAV)
DOI:	https://doi.org/10.1016/j.nut.2023.112264
Versão da editora:	https://www.sciencedirect.com/science/article/pii/S0899900723002927?via%3Dihub
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