Campo DC | Valor | Idioma |
dc.contributor.author | Costa, Vivaldo Gomes da | - |
dc.contributor.author | Saivish, Marielena Vogel | - |
dc.contributor.author | Rodrigues, Roger Luiz | - |
dc.contributor.author | Silva, Rebeca Francielle de Lima | - |
dc.contributor.author | Moreli, Marcos Lázaro | - |
dc.contributor.author | Krüger, Ricardo Henrique | - |
dc.date.accessioned | 2020-10-19T18:07:48Z | - |
dc.date.available | 2020-10-19T18:07:48Z | - |
dc.date.issued | 2019-05-29 | - |
dc.identifier.citation | COSTA, Vivaldo Gomes da et al. Molecular and serological surveys of canine distemper virus: a meta-analysis of cross-sectional studies. PLoS ONE, v. 14, n. 5, e0217594, 2019. DOI: https://doi.org/10.1371/journal.pone.0217594. Disponível em: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0217594. Acesso em: 19 out. 2020. | pt_BR |
dc.identifier.uri | https://repositorio.unb.br/handle/10482/39557 | - |
dc.language.iso | Inglês | pt_BR |
dc.publisher | PLoS ONE | pt_BR |
dc.rights | Acesso Aberto | pt_BR |
dc.title | Molecular and serological surveys of canine distemper virus : a meta-analysis of crosssectional studies | pt_BR |
dc.type | Artigo | pt_BR |
dc.subject.keyword | Cão - doenças | pt_BR |
dc.subject.keyword | Cinomose canina | pt_BR |
dc.subject.keyword | Morbillivírus | pt_BR |
dc.rights.license | Copyright: © 2019 Costa et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | pt_BR |
dc.identifier.doi | https://doi.org/10.1371/journal.pone.0217594 | pt_BR |
dc.description.abstract1 | Background
Canine morbillivirus (canine distemper virus, CDV) persists as a serious threat to the health
of domestic dogs and wildlife. Although studies have been conducted on the frequency and
risk factors associated with CDV infection, there are no comprehensive data on the current
epidemiological magnitude in the domestic dog population at regional and national levels.
Therefore, we conducted a cross-sectional study and included our results in a meta-analysis
to summarize and combine available data on the frequency and potential risk factors associated with CDV infection.
Methods
For the cross-sectional study, biological samples from dogs suspected to have canine distemper (CD) were collected and screened for viral RNA. Briefly, the PRISMA protocol was
used for the meta-analysis, and data analyses were performed using STATA IC 13.1
software.
Results
CDV RNA was detected in 34% (48/141) of dogs suspected to have CD. Following our
meta-analysis, 53 studies were selected for a total of 11,527 dogs. Overall, the pooled frequency of CDV positivity based on molecular and serological results were 33% (95% CI:
23–43) and 46% (95% CI: 36–57), respectively. The pooled subgroup analyses of clinical
signs, types of biological samples, diagnostic methods and dog lifestyle had a wide range of
CDV positivity (range 8–75%). Free-ranging dogs (OR: 1.44, 95% CI: 1.05–1.97), dogs >24
months old (OR: 1.83, 95% CI: 1.1–3) and unvaccinated dogs (OR: 2.92, 95% CI: 1.26–
6.77) were found to be positively associated with CDV infection. In contrast, dogs <12
months old (OR: 0.36, 95% CI: 0.20–0.64) and dogs with a complete anti-CDV vaccination
(OR: 0.18, 95% CI: 0.05–0.59) had a negative association. Conclusion
Considering the high frequency of CDV positivity associated with almost all the variables
analyzed in dogs, it is necessary to immediately and continuously plan mitigation strategies
to reduce the CDV prevalence, especially in determined endemic localities. | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0002-9359-0198 | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0002-7627-621X | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0001-8042-4636 | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0003-4637-211X | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0002-9599-361X | pt_BR |
Aparece nas coleções: | Artigos publicados em periódicos e afins
|