Título:	The impact of sarcopenic obesity on inflammation, lean body mass, and muscle strength in elderly women
Autor(es):	Nascimento, Dahan da Cunha Oliveira, Samuel da Cunha Vieira, Denis Cesar Leite Funghetto, Silvana Schwerz Silva, Alessandro Oliveira Valduga, Renato Schoenfeld, Brad Jon Prestes, Jonato
Assunto:	Sarcopenia Obesidade Massa muscular Obesidade sarcopênica Idosos
Data de publicação:	22-Nov-2018
Editora:	Dove Medical Press
Referência:	NASCIMENTO, Dahan da Cunha et al. The impact of sarcopenic obesity on inflammation, lean body mass, and muscle strength in elderly women. International Journal of General Medicine, n. 11, p. 443-449, nov. 2018. DOI https://doi.org/10.2147/IJGM.S187285. Disponível em: https://www.dovepress.com/the-impact-of-sarcopenic-obesity-on-inflammation-lean-body-mass-and-mu-peer-reviewed-article-IJGM. Acesso em: 26 mar. 2020.
Abstract:	Objective: The objective of this study was to apply the newly standardized definition for sarcopenia from the Foundation for the National Institutes of Health (FNIH) and the current definition for obesity to 1) determine the prevalence of sarcopenic obesity (SO) in obese elderly women; 2) compare the muscle strength, lean body mass, and markers of inflammation between obese elderly women with SO and nonsarcopenic obesity (NSO), and 3) elucidate the relationship between appendicular lean mass adjusted for body mass index (aLM/BMI) with muscle strength, lean body mass, and obesity indices. Methods: A total of 64 elderly obese women (age: 68.35±6.04 years) underwent body composition analysis by dual-energy X-ray absorptiometry. Participants were classified into two groups according to the definition of SO and NSO. Blood samples were collected for total cholesterol, triglycerides, high-density lipoprotein, low-density lipoprotein, uric acid, urea, interleukin-6 (IL-6), glucose, and creatine kinase (CK) measurements. Results: The SO group presented a significantly greater BMI, fat (%), glucose, a marginal trend toward significance for uric acid, and IL-6 compared to the NSO group. In addition, the SO group displayed lower values for muscle strength and lean body mass. From a correlation standpoint, a higher aLM/BMI was positively associated with lean body mass and muscle strength and negatively associated with a lower BMI and percentage body fat. Conclusion: The definition criteria from FNIH and obesity permit the ability to illustrate the prevalence and identify SO in elderly women with low muscle mass, low muscle strength, and impaired markers of inflammation.
Unidade Acadêmica:	Faculdade UnB Ceilândia (FCE) Curso de Enfermagem (FCE-ENF)
Licença:	© 2018 Nascimento et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms. php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php)
DOI:	https://doi.org/10.2147/IJGM.S187285
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