Skip navigation
Universidade de Brasília
Por favor, use este identificador para citar o enlazar este ítem: http://repositorio.unb.br/handle/10482/55473
Ficheros en este ítem:
No hay ficheros asociados a este ítem.
Registro completo de metadatos
Campo DC Valor Lengua/Idioma
dc.contributor.authorKogawa, Evelyn Mikaela-
dc.contributor.authorMelo, Fabíola Ferreira-
dc.contributor.authorPires, Reuel Gomes-
dc.contributor.authorCaetano, Paulo César Candeia-
dc.contributor.authorRodrigues, Jhonatan de Lima-
dc.contributor.authorBenito, Linconl Agudo Oliveira-
dc.contributor.authorSilva, Izabel Cristina Rodrigues da-
dc.contributor.authorCantuária, Ana Paula de Castro-
dc.contributor.authorPeres, Silvia Helena Sales-
dc.date.accessioned2026-07-22T12:39:24Z-
dc.date.available2026-07-22T12:39:24Z-
dc.date.issued2024-02-21-
dc.identifier.citationKOGAWA, Evelyn Mikaela et al. The changes on salivary flow rates, buffering capacity and chromogranin a levels in adults after bariatric surgery. Clinical Oral Investigations, [S. l.], v. 28, n. 3, 159, 2024. DOI: https://doi.org/10.1007/s00784-024-05551-3. Disponível em: https://link.springer.com/article/10.1007/s00784-024-05551-3.pt_BR
dc.identifier.urihttps://doi.org/10.1007/s00784-024-05551-3pt_BR
dc.identifier.urihttp://repositorio.unb.br/handle/10482/55473-
dc.language.isoengpt_BR
dc.publisherSpringer Science and Business Media LLCpt_BR
dc.rightsAcesso Restritopt_BR
dc.titleThe changes on salivary flow rates, buffering capacity and chromogranin a levels in adults after bariatric surgerypt_BR
dc.typeArtigopt_BR
dc.subject.keywordCirurgia bariátricapt_BR
dc.subject.keywordFluxo salivarpt_BR
dc.subject.keywordSalivapt_BR
dc.subject.keywordCromogranina Apt_BR
dc.subject.keywordOdontologiapt_BR
dc.subject.keywordELISA (Ensaio de Imunoadsorção Enzimática)pt_BR
dc.identifier.doihttps://doi.org/10.1007/s00784-024-05551-3pt_BR
dc.relation.publisherversionhttps://link.springer.com/article/10.1007/s00784-024-05551-3pt_BR
dc.description.abstract1Objectives This study aimed to investigate changes in salivary flow rates, buffering capacity, and salivary chromogranin A (CHGA) levels in adults undergoing bariatric surgery (BS) compared with a non-obese control group. Materials and methods Salivary analyses were performed on 62 participants aged over 50 years, stratified into two groups matched for age and gender—individuals who had undergone bariatric surgery (BS) (n = 31) and a corresponding healthy control group (n = 31). Before saliva collection, participants completed a comprehensive 11-point visual numerical rating scale (NRS 0–10) xerostomia questionnaire, assessing subjective perceptions of two key aspects: dryness of the oral mucosa and resultant impact on oral functional ability. Three distinct saliva measurements were obtained: unstimulated whole saliva (UWS), stimulated whole saliva (SWS), and unstimulated upper labial saliva (ULS). The buffering capacity of unstimulated saliva was assessed using pH indicator strips, and concentrations of salivary Chromogranin A (CHGA) were quantified in stimulated saliva via enzyme-linked immunosorbent assay (ELISA). Results After BS, more than 40% of BS group patients reported xerostomia, with 16.1% experiencing only mild symptoms without significant functional impact (p = 0.009). The prevalence of xerostomia and tongue dryness was higher in the BS group compared to the control group (p = 0.028 and p = 0.025, respectively). The comparative analysis unveiled no statistically significant differences in flow rates of unstimulated upper labial saliva (ULS), unstimulated whole saliva (UWS), and stimulated whole saliva (SWS) between the control group and patients who underwent bariatric surgery. However, in patients undergone BS with xerostomia, both ULS and UWS flow rates were significantly lower than in controls with xerostomia (p = 0.014 and p = 0.007, respectively). The buffering capacity was significantly lower in patients undergone BS than in controls (p = 0.009). No differences were found between groups regarding CHGA concentration and output values, nevertheless, higher values of CHGA concentrations were significantly correlated to lower flow rates. Conclusion According to the results, this study suggests that individuals undergoing BS may exhibit altered salivary buffering capacity and reduced unstimulated salivary flows in the presence of xerostomia. Additionally, the findings suggest that elevated concentration of salivary CHGA might be associated, in part, with salivary gland hypofunction.pt_BR
dc.contributor.affiliationUniversidade de São Paulo, Faculdade de Odontologia de Baurupt_BR
dc.contributor.affiliationUniversidade de Brasília, Faculdade de Ciências da Saúde, Departamento de Odontologiapt_BR
dc.contributor.affiliationUniversidade de Brasília, Programa de Pós-Graduação em Odontologiapt_BR
dc.contributor.affiliationUniversidade de Brasília, Programa de Pós-Graduação em Odontologiapt_BR
dc.contributor.affiliationUniversidade Católica de Brasília, Curso de Odontologiapt_BR
dc.contributor.affiliationUniversidade Católica de Brasília, Curso de Odontologiapt_BR
dc.contributor.affiliationUniversidade de Brasília, Pós-Graduação em Ciências e Tecnologias em Saúdept_BR
dc.contributor.affiliationUniversidade de Brasília, Faculdade UnB Ceilândiapt_BR
dc.contributor.affiliationUniversidade de Brasília, Pós-Graduação em Ciências e Tecnologias em Saúdept_BR
dc.contributor.affiliationUniversidade de São Paulo, Faculdade de Odontologia de Baurupt_BR
dc.description.unidadeFaculdade de Ciências da Saúde (FS)pt_BR
dc.description.unidadeDepartamento de Odontologia (FS ODT)pt_BR
dc.description.unidadeFaculdade de Ciências e Tecnologias em Saúde (FCTS) – Campus UnB Ceilândiapt_BR
dc.description.ppgPrograma de Pós-Graduação em Odontologiapt_BR
dc.description.ppgPós-Graduação em Ciências e Tecnologias em Saúdept_BR
Aparece en las colecciones: Artigos publicados em periódicos e afins

Mostrar el registro sencillo del ítem " class="statisticsLink btn btn-primary" href="/handle/10482/55473/statistics">



Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.