Drugs, pesticides and metabolites in forensic post-mortem blood samples

Ferrari Júnior, Ettore; Santos, João Batista Afonso dos; Caldas, Eloisa Dutra

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dc.contributor.author	Ferrari Júnior, Ettore	pt_BR
dc.contributor.author	Santos, João Batista Afonso dos	pt_BR
dc.contributor.author	Caldas, Eloisa Dutra	pt_BR
dc.date.accessioned	2026-07-08T15:21:27Z	-
dc.date.available	2026-07-08T15:21:27Z	-
dc.date.issued	2021-4	pt_BR
dc.identifier.citation	FERRARI JÚNIOR, Ettore; SANTOS, João Batista Afonso dos; CALDAS, Eloisa Dutra. Drugs, pesticides and metabolites in forensic post-mortem blood samples. Medicine, Science and the Law, [S. l.], v. 61, n. 2, p. 97-104, 2021. DOI: https://doi.org/10.1177/0025802420965006.	pt_BR
dc.identifier.uri	https://doi.org/10.1177/0025802420965006	pt_BR
dc.identifier.uri	http://repositorio.unb.br/handle/10482/55295	-
dc.language.iso	eng	-
dc.publisher	SAGE Publications	pt_BR
dc.rights	Acesso Restrito	pt_BR
dc.title	Drugs, pesticides and metabolites in forensic post-mortem blood samples	pt_BR
dc.type	Artigo	pt_BR
dc.subject.keyword	Drogas	-
dc.subject.keyword	Pesticidas	-
dc.subject.keyword	Toxicologia forense	-
dc.subject.keyword	Toxicologia postmortem	-
dc.identifier.doi	https://doi.org/10.1177/0025802420965006	pt_BR
dc.relation.publisherversion	https://journals.sagepub.com/doi/10.1177/0025802420965006	-
dc.description.abstract1	Forensic post-mortem toxicological data provide valuable information for the elucidation of cause of death. However, this is still not routine practice in Brazilian laboratories. This study investigated the presence of illicit and prescription drugs, pesticides and metabolites in 111 post-mortem blood samples from cases investigated by the Forensic Medical Institute of the Federal District, Brazil. Quantitative analysis was performed for 14 analytes using a validated programmed temperature vaporisation-large volume injection-gas chromatography–mass spectrometry method, which was also used as screening (qualitative analysis) for an additional 19 substances of forensic interest. At least one analyte was found in 61.2% of the samples, of which 34 were related to homicide, 15 to accidental death and 10 to suicide cases. The victims were 14–72 years old. The benzodiazepines diazepam, midazolam and 7-aminoflunitrazepan were detected in 46% of the positive samples (0.02–1.12 µg/mL; midazolam only qualitative). Cocaine was found in 34% (0.02–4.07 µg/mL), associated with substances commonly used as cocaine adulterants (e.g. caffeine, lidocaine and phenacetin). Three suicide cases involved the illegal rodenticide chumbinho, residues of which were found in the gastric content, and blood samples showed the presence of terbufos (0.03 and 0.04 µg/mL) and carbofuran (27.3 µg/mL). These results are discussed, along with autopsy and crime-scene information.	pt_BR
dc.identifier.orcid	https://orcid.org/0000-0002-7197-6807	pt_BR
dc.contributor.affiliation	Criminalistics Institute, Forensic Analysis Laboratory, Brazil	pt_BR
dc.contributor.affiliation	University of Brasilia, Department of Pharmacy, Laboratory of Toxicology	pt_BR
dc.contributor.affiliation	Forensic Medicine Institute, Laboratory of Toxicology, Brazil	pt_BR
dc.contributor.affiliation	University of Brasilia, Department of Pharmacy, Laboratory of Toxicology	pt_BR
dc.description.unidade	Faculdade de Ciências da Saúde (FS)	-
dc.description.unidade	Departamento de Farmácia (FS FAR)	-
dc.description.ppg	Programa de Pós-Graduação em Ciências Farmacêuticas	-
Collection(s) :	Artigos publicados em periódicos e afins