Título:	Health-related quality of life among celiacs in Portugal : a comparison between general and specific questionnaires
Autor(es):	Chaves, Cláudia Zandonadi, Renata Puppin Raposo, António Nakano, Eduardo Yoshio Ramos, Fernando Farage, Priscila Lemos, Edite Teixeira
Afiliação do autor:	Polytechnic University of Viseu, Centre for Studies in Education and Innovation University of Brasília, Faculty of Health Sciences, Nutrition Department Research Center for Biosciences and Health Technologies, Universidade Lusófona de Humanidades e Tecnologias University of Brasília, Department of Statistics University of Coimbra, Faculty of Pharmacy Associated Laboratory for Green Chemistry of the Network of Chemistry and Technology Federal University of Goiás, Faculty of Nutrition Polytechnic University of Viseu, CERNAS Research Centre
Assunto:	Doença celíaca Dieta sem glúten Portugal Qualidade de vida Questionários
Data de publicação:	Mar-2024
Editora:	Frontiers in Immunology
Referência:	CHAVES, Cláudia et. al. (2024) Health-related quality of life among celiacs in Portugal: a comparison between general and specific questionnaires. Front. Immunol, [S. l.], v. 15, 1372369, 2024. DOI: 10.3389/fimmu.2024.1372369. Disponível em: https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1372369/full. Acesso em: 14 abr. 2026
Abstract:	Objective: This study aimed to compare the 36-Item Short Form Survey Instrument version 2 (SF-36-v2) (generic) and Celiac Disease Questionnaire (CDQ) (specific) questionnaires used to evaluate the quality of life (QoL) in celiac Portuguese adult individuals. Methods: This cross-sectional study used non-probabilistic sampling based on Portuguese celiac patients who accessed the online survey in 2022. The online data collection used a self-reported instrument composed of three parts: (i) socioeconomic, health, and gluten-free diet (GFD) adherence questions; (ii) SF 36 v2– Portuguese version (generic questionnaire) and (iii) Celiac Disease Questionnaire (CDQ) (specific questionnaire). Results: A total of 234 individuals who accessed the survey completed the questionnaire. Seven of the eight SF-36 domains positively correlated to the specific questionnaire CDQ. The “General Health” domain (domain 4) showed a negative correlation with the CDQ. Differences in content between the two instruments might be able to explain this finding since the CDQ explores issues regarding the specificities of celiac disease (CD) and the lifelong GFD burden. About half of the sample from this study displayed poor diet adherence, it is possible that the SF-36 could not reflect the impact of CD treatment- the complete elimination of gluten from the diet- on patients’ health. Therefore, this issue should be carefully evaluated in future research. Conclusion: Specific validated questionnaires for CD individuals, such as the CDQ, contemplate social, economic, and clinical variables that permeate the patient’s life context. Therefore, these instruments may be more suitable for
Unidade Acadêmica:	Faculdade de Ciências da Saúde (FS) Instituto de Ciências Exatas (IE) Departamento de Nutrição (FS NUT)
Programa de pós-graduação:	Programa de Pós-Graduação em Nutrição Humana
Licença:	2024 Chaves, Zandonadi, Raposo, Nakano, Ramos, Farage and Teixeira-Lemos. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
DOI:	10.3389/fimmu.2024.1372369
Versão da editora:	https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1372369/full
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