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dc.contributor.authorFarias, Jade Ormondes de-
dc.contributor.authorRezende, Taia Maria Berto-
dc.date.accessioned2024-06-07T15:37:15Z-
dc.date.available2024-06-07T15:37:15Z-
dc.date.issued2023-
dc.identifier.citationFARIAS, Jade Ormondes de; REZENDE, Taia Maria Berto. Dental pulp and apical papilla cells senescence: causes, consequences, and prevention. Biogerontology, [S. l.], v. 24, p. 533–539, 2023. DOI: https://doi.org/10.1007/s10522-023-10029-y.pt_BR
dc.identifier.urihttp://repositorio.unb.br/handle/10482/48175-
dc.language.isoengpt_BR
dc.publisherSpringer Nature B.Vpt_BR
dc.rightsAcesso Restritopt_BR
dc.titleDental pulp and apical papilla cells senescence : causes, consequences, and preventionpt_BR
dc.typeArtigopt_BR
dc.subject.keywordSenescência celularpt_BR
dc.subject.keywordPolpa dentáriapt_BR
dc.subject.keywordPapila apicalpt_BR
dc.identifier.doihttps://doi.org/10.1007/s10522-023-10029-ypt_BR
dc.relation.publisherversionhttps://link.springer.com/article/10.1007/s10522-023-10029-ypt_BR
dc.description.abstract1Dental pulp under physiological condi tions has a defense function, repair capacity, and important mechanisms in pathological processes. In addition, the dental papilla is involved in important defense processes and an essential function in the pulp revascularization process. It is known that dental pulp and apical papilla undergo a natural aging process, in addition to stressful situations such as bruxism, infammation, and infections. Both aging and stressful situations can lead to cellular senescence. Some evidence indicates that the changes resulting from this cellular state can directly afect the ef ciency of cells in these tissues and afect conservative and regenerative clinical treatments. Thus, it is nec essary to understand the causes and consequences o cellular senescence in addition to the development of methods for senescence prevention. This review aims to provide an overview of possible causes and conse quences of senescence in dental pulp and stem cells from apical papilla and discusses possible methods to prevent this cellular state.pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9347-3330pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-4148-0659pt_BR
dc.contributor.affiliationUniversidade de Brasília, Faculdade de Ciências de Saúde, Pós-graduação em Ciências da Saúdept_BR
dc.contributor.affiliationUniversidade de Brasília, Faculdade de Ciências de Saúde, Pós-graduação em Ciências da Saúdept_BR
dc.contributor.affiliationUniversidade Católica de Brasília, Curso de Odontologiapt_BR
dc.contributor.affiliationUniversidade Católica de Brasília, Pós-graduação em Ciências Genômicas e Biotecnologiapt_BR
dc.description.unidadeFaculdade de Ciências da Saúde (FS)pt_BR
dc.description.unidadeDepartamento de Odontologia (FS ODT)pt_BR
dc.description.ppgPrograma de Pós-Graduação em Ciências da Saúdept_BR
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