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Title: Recovery of renal function in clinical patients with acute kidney injury : impact on mortality
Authors: Duarte, Tayse Tâmara da Paixão
Magro, Marcia Cristina Silva
metadata.dc.contributor.email: mailto:taysepaixao@unb.br
mailto:marciamagro@unb.br
metadata.dc.identifier.orcid: https://orcid.org/0000-0003-1608-618X
Assunto:: Lesão renal aguda
Rins - doenças - recuperação
Issue Date: 8-Jun-2022
Publisher: MDPI
Citation: DUARTE, Tayse Tâmara Paixão; MAGRO, Marcia Cristina Silva. Recovery of renal function in clinical patients with acute kidney injury: impact on mortality. Life, Basel, v. 12, n. 6, art. 852, 2022. DOI 10.3390/life12060852. Disponível em: https://www.mdpi.com/2075-1729/12/6/852. Acesso em: 05 ago. 2022.
Abstract: Objective: To assess the different renal function recovery patterns and their impact on the mortality of non-critical patients with hospital-acquired Acute Kidney Injury. Design: A prospective cohort study was conducted from January 2017 to December 2019. Methods: The patients included were those with Acute Kidney Injury acquired during their hospitalization, identified from Kidney Disease: Improving Global Outcomes (KDIGO). Renal function recovery was calculated through the serum creatinine ratio in relation to baseline creatinine at the renal function evaluation moment. A descriptive analysis of the results was performed, and the Backward method was adopted for the multivariate analysis. Results: One-thousand five-hundred and forty-six patients were evaluated in the medical clinic and 202 (13.06%) were identified to have Acute Kidney Injury; among them, renal function recovery varied over the six months of follow-up with greater expressiveness in the second and third months (from 61.02% to 62.79%). Recovery was a protective factor against in-hospital death in the first (OR 0.24; 95% CI 0.09–0.61; p-value = 0.038) and sixth month of follow-up (OR 0.24; 95% CI 0.09–0.61; p-value = 0.003). Conclusions: The incidence of renal function recovery varied throughout the six months of follow-up and reached progressively high levels from the second to the third months. Renal recovery was a protective factor against mortality during the follow-up period.
Licença:: Life - Articles published in Life will be Open-Access articles distributed under the terms and conditions of the Creative Commons Attribution License (CC BY). The copyright is retained by the author(s). MDPI will insert the following note at the end of the published text: © 2022 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). Fonte: https://www.mdpi.com/journal/life/about. Acesso em: 05 ago. 2022.
DOI: https://doi.org/10.3390/life12060852
Appears in Collections:FCE-ENF - Artigos publicados em periódicos

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