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Title: The impact of sarcopenic obesity on inflammation, lean body mass, and muscle strength in elderly women
Authors: Nascimento, Dahan da Cunha
Oliveira, Samuel da Cunha
Vieira, Denis Cesar Leite
Funghetto, Silvana Schwerz
Silva, Alessandro Oliveira
Valduga, Renato
Schoenfeld, Brad Jon
Prestes, Jonato
Assunto:: Sarcopenia
Massa muscular
Obesidade sarcopênica
Issue Date: 22-Nov-2018
Publisher: Dove Medical Press
Citation: NASCIMENTO, Dahan da Cunha et al. The impact of sarcopenic obesity on inflammation, lean body mass, and muscle strength in elderly women. International Journal of General Medicine, n. 11, p. 443-449, nov. 2018. DOI Disponível em: Acesso em: 26 mar. 2020.
Abstract: Objective: The objective of this study was to apply the newly standardized definition for sarcopenia from the Foundation for the National Institutes of Health (FNIH) and the current definition for obesity to 1) determine the prevalence of sarcopenic obesity (SO) in obese elderly women; 2) compare the muscle strength, lean body mass, and markers of inflammation between obese elderly women with SO and nonsarcopenic obesity (NSO), and 3) elucidate the relationship between appendicular lean mass adjusted for body mass index (aLM/BMI) with muscle strength, lean body mass, and obesity indices. Methods: A total of 64 elderly obese women (age: 68.35±6.04 years) underwent body composition analysis by dual-energy X-ray absorptiometry. Participants were classified into two groups according to the definition of SO and NSO. Blood samples were collected for total cholesterol, triglycerides, high-density lipoprotein, low-density lipoprotein, uric acid, urea, interleukin-6 (IL-6), glucose, and creatine kinase (CK) measurements. Results: The SO group presented a significantly greater BMI, fat (%), glucose, a marginal trend toward significance for uric acid, and IL-6 compared to the NSO group. In addition, the SO group displayed lower values for muscle strength and lean body mass. From a correlation standpoint, a higher aLM/BMI was positively associated with lean body mass and muscle strength and negatively associated with a lower BMI and percentage body fat. Conclusion: The definition criteria from FNIH and obesity permit the ability to illustrate the prevalence and identify SO in elderly women with low muscle mass, low muscle strength, and impaired markers of inflammation.
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Appears in Collections:FCE-ENF - Artigos publicados em periódicos

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