| Campo DC | Valor | Lengua/Idioma |
|---|
| dc.contributor.author | Costa, Gabriella Gusmão Pereira da | pt_BR |
| dc.contributor.author | Silva, Cristian Aldemar Gasca | pt_BR |
| dc.contributor.author | Gomes, João Victor Dutra | pt_BR |
| dc.contributor.author | Torres, Amanda Gomes | pt_BR |
| dc.contributor.author | Santos, Izulmé Rita Imaculada | pt_BR |
| dc.contributor.author | Almeida, Fabrício Tavares Cunha de | pt_BR |
| dc.contributor.author | Fagg, Christopher William | pt_BR |
| dc.contributor.author | Simeoni, Luiz Alberto | pt_BR |
| dc.contributor.author | Silveira, Dâmaris | pt_BR |
| dc.contributor.author | Gomes-Copeland, Kicia Karinne Pereira | pt_BR |
| dc.date.accessioned | 2020-01-24T10:30:21Z | - |
| dc.date.available | 2020-01-24T10:30:21Z | - |
| dc.date.issued | 2019 | pt_BR |
| dc.identifier.citation | COSTA, Gabriella Gusmão Pereira da et al. Influence of in vitro micropropagation on lycorine biosynthesis and anticholinesterase activity in Hippeastrum goianum. Revista Brasileira de Farmacognosia, v. 29, n. 2, p. 262-265, 2019. DOI: https://doi.org/10.1016/j.bjp.2019.02.001. Disponível em: http://scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2019000200262. Acesso em: 23 jan.2020. | pt_BR |
| dc.identifier.uri | https://repositorio.unb.br/handle/10482/36338 | - |
| dc.language.iso | en | pt_BR |
| dc.publisher | Sociedade Brasileira de Farmacognosia | pt_BR |
| dc.rights | Acesso Aberto | pt_BR |
| dc.title | Influence of in vitro micropropagation on lycorine biosynthesis and anticholinesterase activity in Hippeastrum goianum | pt_BR |
| dc.type | Artigo | pt_BR |
| dc.subject.keyword | Alcalóides | pt_BR |
| dc.subject.keyword | Biossíntese | pt_BR |
| dc.subject.keyword | Cromatografia a líquido | pt_BR |
| dc.subject.keyword | Licorina | pt_BR |
| dc.subject.keyword | Espectrometria de massa | - |
| dc.rights.license | This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/). | - |
| dc.identifier.doi | https://doi.org/10.1016/j.bjp.2019.02.001 | pt_BR |
| dc.description.abstract1 | Hippeastrum goianum (Ravenna) Meerow, Amaryllidaceae, is an endemic species from the Cerrado, Brazil; there are only few studies about its chemistry or biological activity. This study aimed to investigate the occurrence of lycorine in extracts from in vitro H. goianum plantlets, as well as evaluate a possible inhibition of acetylcholinesterase. The ethanol extract of plantlets produced by in vitro seed germination and micropropagation of bulblets was obtained from seedlings from in vitro germination, while the ethanol extract micropropagtion of bulblets was obtained from a subculture of those seedlings. The presence of lycorine was detected in only in the micropropagation of bulblets. The micropropagation of bulblets was more active than the plantlets produced by in vitro seed germination, with an IC50 of 114.8 ± 0.95 µg/ml and IC50 386.00 ± 0.97 µg/ml, respectively. These results showed that both in vitro germination and micropropagation of H. goianum can lead to the biosynthesis of lycorine. Moreover, the micropropagation led to improved anticholinesterase activity. | - |
| dc.identifier.orcid | http://orcid.org/0000-0002-3393-5609 | - |
| dc.identifier.orcid | http://orcid.org/0000-0003-4392-4230 | - |
| dc.identifier.orcid | http://orcid.org/0000-0001-6098-3852 | - |
| dc.identifier.orcid | http://orcid.org/0000-0001-9599-4578 | - |
| dc.identifier.orcid | http://orcid.org/0000-0002-1503-1497 | - |
| dc.identifier.orcid | http://orcid.org/0000-0002-0531-7483 | - |
| dc.identifier.orcid | http://orcid.org/0000-0001-6072-7832 | - |
| dc.identifier.orcid | http://orcid.org/0000-0003-3401-290X | - |
| dc.identifier.orcid | http://orcid.org/0000-0003-1851-5224 | - |
| dc.identifier.orcid | http://orcid.org/0000-0003-3539-2916 | - |
| Aparece en las colecciones: | Artigos publicados em periódicos e afins
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