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Title: Time trends and changes in the distribution of malaria cases in the Brazilian Amazon Region, 2004-2013
Authors: Lima, Isac da Silva Ferreira
Mesones Lapouble, Oscar Martín
Duarte, Elisabeth Carmen
Assunto:: Malária - epidemiologia
Amazônia - Brasil
Issue Date: Jan-2017
Publisher: Instituto Oswaldo Cruz, Ministério da Saúde
Citation: LIMA, Isac da S. F.; LAPOUBLE, Oscar M. M.; DUARTE, Elisabeth C. Time trends and changes in the distribution of malaria cases in the Brazilian Amazon Region, 2004-2013. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 112, n. 1, p. 8-18, jan. 2017. Disponível em: <>. Acesso em: 22 fev. 2018. Epub Dec 01, 2016. doi:
Abstract: Recent efforts to reduce malaria incidence have had some successes. Nevertheless, malaria persists as a significant public health problem in the Brazilian Amazon. The objective of this study was to describe changes in malaria case characteristics and to identify trends in malaria incidence in the Brazilian Amazon. This study used data from the Malaria Epidemiological Surveillance and Case Notification Information System from 2004 to 2013. The annual parasite incidence (API) was calculated and joinpoint regression was used to assess the trends in API over time. There was a sharp increase in API in the state of Acre, followed by two periods of decrease. Pará also presented inconsistent decreases over the study period. Amapá, Amazonas, Rondônia, and Roraima showed statistically significant decreases over the period. The sharpest decrease occurred in Rondônia, with a reduction of 21.7% in the average annual percent change (AAPC) (AAPC: -21.7%; 95% confidence interval: -25.4%, -17.8%; p < 0.05). This panorama of malaria incidence highlights the importance of integrating evidence-based malaria surveillance and control. Malaria is highly preventable, and eliminating its transmission should be a goal in coming decades.
Licença:: Memórias do Instituto Oswaldo Cruz - This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0). Fonte: Acesso em: 22 fev. 2018.
Appears in Collections:FMD - Artigos publicados em periódicos e preprints

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