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dc.contributor.authorJozala, Angela Faustinopt_BR
dc.contributor.authorGeraldes, Danilo Costapt_BR
dc.contributor.authorTundisi, Louise Lacalendolapt_BR
dc.contributor.authorFeitosa, Valker de Araújopt_BR
dc.contributor.authorBreyer, Carlos Alexandrept_BR
dc.contributor.authorCardoso, Samuel Leitept_BR
dc.contributor.authorMazzola, Priscila Gavapt_BR
dc.contributor.authorOliveira-Nascimento, Laura dept_BR
dc.contributor.authorRangel-Yagui, Carlota de Oliveirapt_BR
dc.contributor.authorMagalhães, Pérola de Oliveirapt_BR
dc.contributor.authorOliveira, Marcos Antonio dept_BR
dc.contributor.authorPessoa Junior, Adalbertopt_BR
dc.date.accessioned2017-12-07T05:18:48Z-
dc.date.available2017-12-07T05:18:48Z-
dc.date.issued2016-12pt_BR
dc.identifier.citationJOZALA, Angela Faustino et al. Biopharmaceuticals from microorganisms: from production to purification. Brazilian Journal of Microbiology, São Paulo, v. 47, supl. 1, p. 51-63, dez. 2016. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000500051&lng=en&nrm=iso>. Acesso em: 20 dez. 2017. doi: http://dx.doi.org/10.1016/j.bjm.2016.10.007.pt_BR
dc.identifier.urihttp://repositorio.unb.br/handle/10482/30365-
dc.language.isoenpt_BR
dc.publisherSociedade Brasileira de Microbiologiapt_BR
dc.rightsAcesso Abertopt_BR
dc.titleBiopharmaceuticals from microorganisms : from production to purificationpt_BR
dc.typeArtigopt_BR
dc.subject.keywordBiofármacospt_BR
dc.subject.keywordProcesso - fermentaçãopt_BR
dc.subject.keywordBiotecnologiapt_BR
dc.rights.licenseBrazilian Journal of Microbiology - This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivative License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited and the work is not changed in any way (CC BY NC ND). Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000500051&lng=en&nrm=iso. Acesso em: 20 dez. 2017.-
dc.identifier.doihttp://dx.doi.org/10.1016/j.bjm.2016.10.007pt_BR
dc.description.abstract1The use of biopharmaceuticals dates from the 19th century and within 5-10 years, up to 50% of all drugs in development will be biopharmaceuticals. In the 1980s, the biopharmaceutical industry experienced a significant growth in the production and approval of recombinant proteins such as interferons (IFN α, β, and γ) and growth hormones. The production of biopharmaceuticals, known as bioprocess, involves a wide range of techniques. In this review, we discuss the technology involved in the bioprocess and describe the available strategies and main advances in microbial fermentation and purification process to obtain biopharmaceuticals.-
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