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Title: Isolated schwannoma of the olfactory groove : a case report
Authors: Nascimento, Luiz Augusto
Settanni, Flávio Aurélio Parente
Góis Filho, José Franscisco de
Sanchez, Isabela Naria Dias
Cavalcante, Bruna Barros
Stávale, João Noberto
Assunto:: Neoplasias
Issue Date: Jan-2015
Publisher: Fundação Otorrinolaringologia
Citation: NASCIMENTO, Luiz Augusto et al. Isolated schwannoma of the olfactory groove: a case report. International Archives of Otorhinolaryngology, São Paulo, v. 19, n. 1, p. 93-95, jan./mar. 2015. Disponível em: <>. Acesso em: 23 mar. 2018. doi:
Abstract: Introduction: schwannoma of the olfactory groove is an extremely rare tumor that can share a differential diagnosis with meningioma or neuroblastoma. Objectives: the authors present a case of giant schwannoma involving the anterior cranial fossa and ethmoid sinuses. Case Report: the patient presented with a 30-month history of left nasal obstruction, anosmia, and sporadic ipsilateral bleeding. Computed tomography of the paranasal sinuses revealed expansive lesion on the left nasal cavity extending to nasopharynx up to ethmoid and sphenoid sinuses bilaterally with intraorbital and parasellar extension to the skull base. Magnetic resonance imaging scan confirmed the expansive tumor without dural penetration. Biopsy revealed no evidence of malignancy and probable neural cell. Bifrontal craniotomy was performed combined with lateral rhinotomy (Weber-Ferguson approach), and the lesion was totally removed. The tumor measured 8.0 4.3 3.7 cm and microscopically appeared as a schwannoma composed of interwoven bundles of elongated cells (Antoni A regions)mixed with less cellular regions (Antoni B). Immunohistochemical study stained intensively for vimentin and S-100. Conclusion Schwannomas of the olfactory groove are extremely rare, and the findings of origin of this tumor is still uncertain but recent studies point most probably to the meningeal branches of trigeminal nerve or anterior ethmoidal nerves.
Licença:: International Archives of Otorhinolaryngology - This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY NC ND 4.0). Fonte: Acesso em: 23 mar. 2018.
Appears in Collections:FMD - Artigos publicados em periódicos e preprints

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