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dc.contributor.authorNovaes, Maria Rita Carvalho Garbipt_BR
dc.contributor.authorValadares, Fabianapt_BR
dc.contributor.authorReis, Mariana Campospt_BR
dc.contributor.authorGonçalves, Daniella Rodriguespt_BR
dc.contributor.authorMenezes, Marilia da Cunhapt_BR
dc.description.abstractBreast cancer is the most prevalent cancer in women. The most frequent therapeutic approaches for the treatment of this disease are chemotherapy, radiotherapy, hormone therapy, and surgery. Conventional pharmacological treatments cause many harmful side effects in patients. To improve the quality of life of breast cancer patients, researchers have sought alternative adjuvant treatment strategies. To assess the effects of fungi and other basidiomycetes Agaricales on the co-adjuvant treatment of breast cancer, we conducted a literary review of the available scientific evidence. We selected articles published in refereed journals from 1990 to 2011 in Medline, Lilacs, CAPES, Scielo, and Pubmed. Articles written in English, Spanish, and Portuguese were reviewed. We used the following descriptors: Agaricales, medicinal mushroom/fungus, breast cancer, dietary supplementation, synonyms, and related terms. The pharmacological effects of nutritional and medicinal mushrooms have been reported in several experimental clinical studies and have shown promising results in the adjuvant treatment of breast cancer. Adjuvant treatment with mushrooms is associated with improvements in the immunological and hematologic parameters of breast cancer, as well as in the quality of life of these patients. Randomized clinical studies are needed to elucidate the possible mechanisms of action and clinical benefits of these fungi with respect to survival time, disease progression, and metastasis in breast cancer.pt_BR
dc.publisherFaculdade de Medicina / USPpt_BR
dc.rightsAcesso Abertopt_BR
dc.titleThe effects of dietary supplementation with Agaricales mushrooms and other medicinal fungi on breast cancer: evidence-based medicinept_BR
dc.subject.keywordNutritional supplementpt_BR
dc.subject.keywordAgaricus sylvaticuspt_BR
dc.subject.keywordMedicinal mushroompt_BR
dc.subject.keywordAdjuvant treatmentpt_BR
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