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Title: Distribution of glutathione S-transferase GSTM1 and GSTT1 null phenotypes in Brazilian Amerindians
Authors: Guimarães, Maria de Nazaré Klautau
Hiragi, Cássia de Oliveira
D'Ascenção, Renata Ferreira
Oliveira, Silviene Fabiana de
Grisolia, Cesar Koppe
Hatagima, Ana
Ferrari, Íris
Assunto:: Índios Munduruku
Índios Kaiabi
Alelos
Glutathione S-transferase
Issue Date: Mar-2005
Publisher: Sociedade Brasileira de Genética
Citation: KLAUTAU-GUIMARAES, Maria de Nazaré et al. Distribution of glutathione S-transferase GSTM1 and GSTT1 null phenotypes in Brazilian Amerindians. Genetics and Molecular Biology, São Paulo, v. 28, n. 1, p. 32-35, mar. 2005. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000100005&lng=en&nrm=iso>. Acesso em: 25 out. 2017. doi: http://dx.doi.org/10.1590/S1415-47572005000100005.
Abstract: The distribution of glutathione S-transferase (GST) GSTM1 and GSTT1 null phenotype frequencies in two Brazilian Amerindian tribes, the Munduruku tribe from Missão Cururu village (79 individuals) and the Kayabi tribe (41 individuals), was analyzed by polymerase chain reaction (PCR) amplification. The GST null phenotype frequencies for the Munduruku sample were 0% for GSTM1 and 27% for GSTT1 while for the Kayabi sample the null phenotype frequencies were 27% for GSTM1 and 29% for GSTT1. This is the first report of the absence of the GSTM1 null phenotype in any ethnic group.
Licença:: Genetics and Molecular Biology - All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License (CC BY NC). Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000100005&lng=en&nrm=iso. Acesso em: 25 out. 2017.
DOI: http://dx.doi.org/10.1590/S1415-47572005000100005
Appears in Collections:GEM - Artigos publicados em periódicos

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