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dc.contributor.authorGomes, Anderson de Jesus-
dc.contributor.authorLunardi, Claure Nain-
dc.contributor.authorGonzalez, Salvador-
dc.contributor.authorTedesco, Antonio Claudio-
dc.identifier.citationGOMES, A.J. et al. The antioxidant action of Polypodium leucotomos extract and kojic acid: reactions with reactive oxygen species. Brazilian Journal of Medical and Biological Research, Ribeirão Preto, v. 34, n. 11, nov. 2001. Disponível em: <>. Acesso em: 8 nov. 2012.
dc.description.abstractTwo natural products Polypodium leucotomos extract (PL) and kojic acid (KA) were tested for their ability to scavenge reactive oxygen species (•OH, •O2-, H2O2, 1O2) in phosphate buffer. Hydroxyl radicals were generated by the Fenton reaction, and the rate constants of scavenging were 1.6 x 109 M-1 s-1 for KA and 1.0 x 109 M-1 s-1 for PL, similar to that of ethanol (1.4 x 109 M-1 s-1). With superoxide anions generated by the xanthine/hypoxanthine system, KA and PL (0.2-1.0 mg/ml) inhibited •O2-dependent reduction of nitroblue tetrazolium by up to 30 and 31%, respectively. In the detection of 1O2 by rose bengal irradiation, PL at 1.0 mg/ml quenched singlet oxygen by 43% relative to azide and KA by 36%. The present study demonstrates that PL showed an antioxidant effect, scavenging three of four reactive oxygen species tested here. Unlike KA, PL did not significantly scavenge hydrogen peroxide.en
dc.publisherAssociação Brasileira de Divulgação Científicaen
dc.rightsAcesso Abertoen
dc.titleThe antioxidant action of Polypodium leucotomos extract and kojic acid : reactions with reactive oxygen speciesen
dc.subject.keywordRadicais livres (Química)en
dc.subject.keywordÁcido kójicoen
dc.rights.licenseBrazilian Journal of Medical and Biological Research - Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons (Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0)). Fonte: Acesso em: 8 nov. 2012.en
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